Use of intravenous ketamine-midazolam association for pain procedures in children with cancer. A prospective study
| Autor: | Xavier Rialland, J.C. Granry, Isabelle Pellier, P. Le Moine, J. P Monrigal, B. Rod |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.drug_class Sedation Analgesic Surgery Hypnotic Anesthesiology and Pain Medicine Sedative Anesthesia Pediatrics Perinatology and Child Health Medicine Midazolam Ketamine medicine.symptom business Prospective cohort study Complication medicine.drug |
| Zdroj: | Pediatric Anesthesia. 9:61-68 |
| ISSN: | 1460-9592 1155-5645 |
| DOI: | 10.1046/j.1460-9592.1999.9120280.x |
| Popis: | We evaluated the safety and efficacy of midazolam-ketamine association to control pain induced by diagnostic procedures in paediatric oncology patients. 226 procedures were carried out in 92 patients aged three days to 18 years. Drugs were given i.v. by an anaesthesiologist. Midazolam dose was 25 microg.kg-1 and ketamine 0. 5 to 2 mg.kg-1, depending on number and invasiveness of procedures. The mean dose of ketamine was 1 mg.kg-1. Mean duration of sedation was ten min. No complication was observed and analgesia was considered satisfactory in 89 out of 92 patients. These results indicate that midazolam-ketamine is a safe and effective association in pain management for paediatric oncology patients and efficiently induces brief unconscious sedation with analgesia. |
| Databáze: | OpenAIRE |
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