Development of Large-Scale Syntheses of Ropinirole in the Pursuit of a Manufacturing Process1

Autor:	Alan Negus, M. Whiter, and Timothy C. Walsgrove, Simon Howie, John D. Hayler, Paul Oxley, Giles Robert Gordon
Rok vydání:	1998
Předmět:	chemistry.chemical_compound Materials science Ropinirole chemistry Scale (ratio) Hydrochloride Organic Chemistry medicine Ferric Physical and Theoretical Chemistry Chloride medicine.drug Nuclear chemistry
Zdroj:	Organic Process Research & Development. 2:3-9
ISSN:	1520-586X 1083-6160
Popis:	Two plant syntheses of ropinirole {4-[2-(di-n-propylamino)ethyl]-1,3-dihydro-2H-indolin-2-one hydrochloride, SK&F-101468-A} using the ferric chloride mediated cyclisation of β-nitrostyrenes to form...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::66160b2235b8688445b773c10778d553 https://doi.org/10.1021/op970037c Zobrazit plný text záznamu