Syntheses of some 2-hydroxypyrazine 1-oxides
Autor: | Mayumi Tsutsui, Sawako Masano, Sumie Suzuki, Yasuo Akita, Hiromi Makita, Hideo Tamamura, Akihiro Ohta, Fusako Yamamoto |
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Rok vydání: | 1981 |
Předmět: | |
Zdroj: | Journal of Heterocyclic Chemistry. 18:555-558 |
ISSN: | 1943-5193 0022-152X |
DOI: | 10.1002/jhet.5570180323 |
Popis: | A series of 2-hydroxypyrazine 1-oxides were prepared from the corresponding chloropyrazines by two methods, including oxidation processes in satisfactory yields. The treatment of 2,3-diphenylpyrazine 1,4-dioxide (6) led to 2,3-dichloro-5,6-diphenylpyrazine (7) and 2-chloro-5,6-diphenylpyrazine 1-oxide (8), and the latter was converted to 5,6-diphenyl-2-hydroxypyrazine 1-oxide (9) by an alkaline hydrolysis. |
Databáze: | OpenAIRE |
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