Syntheses of some 2-hydroxypyrazine 1-oxides

Autor: Mayumi Tsutsui, Sawako Masano, Sumie Suzuki, Yasuo Akita, Hiromi Makita, Hideo Tamamura, Akihiro Ohta, Fusako Yamamoto
Rok vydání: 1981
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 18:555-558
ISSN: 1943-5193
0022-152X
DOI: 10.1002/jhet.5570180323
Popis: A series of 2-hydroxypyrazine 1-oxides were prepared from the corresponding chloropyrazines by two methods, including oxidation processes in satisfactory yields. The treatment of 2,3-diphenylpyrazine 1,4-dioxide (6) led to 2,3-dichloro-5,6-diphenylpyrazine (7) and 2-chloro-5,6-diphenylpyrazine 1-oxide (8), and the latter was converted to 5,6-diphenyl-2-hydroxypyrazine 1-oxide (9) by an alkaline hydrolysis.
Databáze: OpenAIRE