Interaction of gold nanoparticles with nanosecond laser pulses: Nanoparticle heating
| Autor: | P.A. Atanasov, Nikolay N. Nedyalkov, S.E. Imamova, Elena Gardeva, Marin Alexandrov, L. Yossifova, Minoru Obara, Reneta Toshkova |
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| Rok vydání: | 2011 |
| Předmět: |
Materials science
business.industry Scattering Physics::Medical Physics Analytical chemistry Physics::Optics General Physics and Astronomy Nanoparticle Surfaces and Interfaces General Chemistry Photothermal therapy Nanosecond Condensed Matter Physics Laser Surfaces Coatings and Films law.invention Colloidal gold law Optoelectronics Particle Particle size business |
| Zdroj: | Applied Surface Science. 257:5456-5459 |
| ISSN: | 0169-4332 |
| Popis: | Theoretical and experimental results on the heating process of gold nanoparticles irradiated by nanosecond laser pulses are presented. The efficiency of particle heating is demonstrated by in-vitro photothermal therapy of human tumor cells. Gold nanoparticles with diameters of 40 and 100 nm are added as colloid in the cell culture and the samples are irradiated by nanosecond pulses at wavelength of 532 nm delivered by Nd:YAG laser system. The results indicate clear cytotoxic effect of application of nanoparticle as more efficient is the case of using particles with diameter of 100 nm. The theoretical analysis of the heating process of nanoparticle interacting with laser radiation is based on the Mie scattering theory, which is used for calculation of the particle absorption coefficient, and two-dimensional heat diffusion model, which describes the particle and the surrounding medium temperature evolution. Using this model the dependence of the achieved maximal temperature in the particles on the applied laser fluence and time evolution of the particle temperature is obtained. |
| Databáze: | OpenAIRE |
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