| Autor: |
Göran Smedegård, Björn Revenäs |
| Rok vydání: |
1981 |
| Předmět: |
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| DOI: |
10.1016/b978-0-08-027347-1.50059-1 |
| Popis: |
Publisher Summary This chapter discusses the two cardiorespiratory patterns of anaphylaxis in a monkey. The clinical manifestations of anaphylaxis in man show a considerable variation. One possible explanation for this may be involvement of different types of antibodies. The chapter presents an investigation that was undertaken to study mechanisms inducing shock in anaphylaxis mediated by two types of antibodies. The first type of anaphylaxis was induced in monkeys possessing a high concentration of specific IgG antibodies, and the second type was induced in monkeys having a high concentration of specific IgE antibodies. The experiments were performed under ketamine hydrochloride anesthesia in spontaneously breathing animals. A redistribution of blood flow to the heart and brain at the expense of flow to other organs occurred during both types of anaphylaxis. An initial redistribution of flow within the left ventricular myocardium resulted in a relative decrease in subendocardial flow. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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