Adult T-cell leukemia-lymphoma unusual features of two patients from a low-incidence area

Autor:	Setular Rangan, Melissa G. Brammer, Judith J. Temple, W. Abe Andes, Steve Covington
Rok vydání:	1986
Předmět:	Cancer Research Pathology medicine.medical_specialty biology business.industry Incidence (epidemiology) Fulminant Congenital cytomegalovirus infection medicine.disease Adult T-cell leukemia/lymphoma Lymphoma Leukemia Oncology medicine biology.protein Antibody Sinusitis business
Zdroj:	Cancer. 58:694-698
ISSN:	1097-0142 0008-543X
DOI:	10.1002/1097-0142(19860801)58:3<694::aid-cncr2820580316>3.0.co;2-w
Popis:	The occurrence of adult T-cell leukemia-lymphoma in two New Orleans patients, one native-born, the other originally from Honduras, is reported. Both exhibited an unusual feature. One patient was diagnosed following an atypical episode of sinusitis and demonstrated lymphomatous infiltration of the nasopharynx. A second patient had a fulminant course complicated by severe diarrhea and was found to have both tumor involvement and cytomegalovirus inclusions in the colon. Both had high titers of antibodies to HTLV-I. A cell line with T-lymphocyte characteristics was established from the peripheral blood of the first patient. Such studies may help better establish the clinical course, detection, and epidemiologic features of this difficult disease.Cancer 58:694-698, 1986.
Databáze:	OpenAIRE
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