Oral manifestation and dental management in a patient with chronic graft versus host disease with around a 10-year follow-up
| Autor: | Ladan Jamshidy, Roohollah Sharifi, Mohammad Shooriabi, Hamid Reza Mozaffari, Hedaiat Moradpoor, Masoud Sadeghi, Neda Omidpanah |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry 10 year follow up medicine.medical_treatment 030206 dentistry Hematopoietic stem cell transplantation medicine.disease General Biochemistry Genetics and Molecular Biology Tongue burning Surgery stomatognathic diseases 03 medical and health sciences surgical procedures operative 0302 clinical medicine Graft-versus-host disease immune system diseases hemic and lymphatic diseases Extracorporeal Photopheresis medicine Major complication business 030215 immunology Chronic myelogenous leukemia |
| Zdroj: | Biomedical Research and Therapy. 5:2370-2377 |
| ISSN: | 2198-4093 |
| DOI: | 10.15419/bmrat.v5i6.449 |
| Popis: | Chronic graft versus host disease (cGVHD) is a complex entity and major complication following allogenic hematopoietic stem cell transplantation (allo-HSCT). This study was the first to report oral manifestation and dental management in a patient with cGVHD after allo-HSCT with a longterm follow-up. A 40-year-old man referred to Department of Oral and Maxillofacial Medicine with complaints of tongue burning, mouth dryness, and ulcers. He had chronic myelogenous leukemia and had undergone allo-HSCT. The patient had undergone treatment with several sessions of extracorporeal photopheresis. The GVHD complications had started about nine months after HSCT. In conclusion, the dentist should play a role in the local therapy of cases with oral manifestation and dental management of cGVHD. Controlling the GVHD can reduce oral and dental alterations, increase the improvement of the quality of life, and reduce the need for more intensive immunosuppressive systemic therapies. |
| Databáze: | OpenAIRE |
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