Right Anterior Theta Connectivity Predicts Autistic Social Traits in Neurotypical Children

Autor: Aron T. Hill, Jodie Van Der Elst, Felicity J. Bigelow, Jarrad A. G. Lum, Peter G. Enticott
Rok vydání: 2022
DOI: 10.1101/2022.03.26.485953
Popis: Growing evidence supports functional network alterations in autism spectrum disorder, however much less is known about the neural mechanisms underlying autistic traits in typically developing children. Using resting-state electroencephalographic (EEG) recordings, we examined whether functional connectivity could predict autistic trait expression in 127 children aged between 4-12 years. Regression models showed that right anterior theta connectivity was a significant predictor of autistic traits (p = 0.013), with increased connectivity in this region associated with greater autistic trait expression. These results corroborate similar recent findings in adults, extending this observation to a cohort of children spanning early-to-middle childhood. These findings further highlight EEG-derived functional connectivity as a sensitive physiological correlate of autistic trait expression in neurotypical children.
Databáze: OpenAIRE