Study of the antioxidant and bacterial activity of the flavonic glycosides existing in the plant 'Cynodon Dactylon (L) Pers' by the free radical DPPH and the reduction of iron

Autor: BENZAHI KHEDIDJA, LABED BRAHIM, BENZAHI RABIA, HASSANI ABDELKADER, ZORAI AMEUR, BOUHOREIRA ABDELAZIZ, SERRAOUI MABROUK, BEN ACHOURA SABRINA BATOUL
Rok vydání: 2023
DOI: 10.21203/rs.3.rs-2414186/v1
Popis: The phytotherapy use of Cynodon Dactylon "L" Pers plant in traditional medicine has led us to work on the evaluation of the heteroside extracts of this plant, as well as aiding in the performance of phytochemical screening and the assessment of this plant's antioxidant activity using the "FRAP" method for reducing iron and scavenging DPPH radicals. Furthermore, research on the flavonoid components found in the two plant extracts' antibacterial properties is needed. The antioxidant properties were demonstrated by identifying the effective inhibition concentration IC50 compared by the antioxidant effect of quercitin. The results mentioned that the extract of Ethyl Acetate has a higher activity than that of the Butanol extract "Ethyl Acetate extract IC50 ≃ 0.014 mg/ml, butanol extract IC50 ≃ 0.019 mg/ml". Also, the reducing power at the concentration of 2.5 mg/ml of ethyl acetate extract of Cynodon Dactylon was much higher (Ab=1.376 nm) compared to the Butanol extract (Ab= 1.297nm). On the other hand, the butanol extract exerted weak activity against the referential bacterial strains. However, the ethyl acetate extract of flavonoids exhibited moderately positive activity on only two strains of "Enterococcus faecalis and Streptococcus pyogenes".
Databáze: OpenAIRE