A thermoresponsive crosslinker for reversible micelle stabilization

Autor: Mark Q. Tolentino, Jessica L. Rouge
Rok vydání: 2021
Předmět:
Zdroj: Materials Advances. 2:2267-2271
ISSN: 2633-5409
DOI: 10.1039/d1ma00089f
Popis: Herein we report a thermoresponsive crosslinker that can be utilized to stabilize the surface of micelles through a “click” reaction and to trigger the disassembly via a retro Diels Alder (rDA) mechanism. The micelles generated were 100 nm in size and monodispersed. Above 60 °C, rDA dissociation of crosslinker occurs resulting to the degradation of the micelles and release of hydrophobic cargo.
Databáze: OpenAIRE