SYNTHESIS OF SULPHANILYLTHIOUREA AND RELATED COMPOUNDS

Autor:	Leo Brickman, Bruce E. Baker, Leonard C. Leitch
Rok vydání:	1945
Předmět:	Chemistry Inorganic chemistry Organic chemistry General Medicine Hydrogen sulphide
Zdroj:	Canadian Journal of Research. :139-157
ISSN:	1923-4287
DOI:	10.1139/cjr45b-018
Popis:	A number of attempts to prepare sulphanilylthiourea are described. The synthesis was accomplished by reacting acetylsulphanilylcyanamide with hydrogen sulphide under pressure and at elevated temperatures to form acetylsulphanilylthiourea, which was deacetylated to sulphanilylthiourea. This compound was also prepared directly from sulphanilylcyanamide and ammonium sulphide in a sealed tube. Acetylsulphaguanidine was prepared in an analogous manner by replacing the hydrogen sulphide with ammonium chloride. The conversion of acetylsulphanilylthiourea to sulphathiazole is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::65abde7c02873e9808ce1166a7584c97 https://doi.org/10.1139/cjr45b-018 Zobrazit plný text záznamu