Randomized controlled trial comparing two doses of daily vitamin D supplementation in preterm neonates

Autor: Dina Jamal Abdelmoez Abdelmegeed Basta, Hanna Mohamed Aboulghar, Aliaa Adel Ali, Dina Mohamed Akmal, Heba Nabil Amin Baz
Rok vydání: 2022
Předmět:
Zdroj: International journal of health sciences. 6:186-203
ISSN: 2550-696X
2550-6978
DOI: 10.53730/ijhs.v6ns1.4760
Popis: Vitamin D supplementation is recommended for preterm infants. The study aimed to compare the effect of 400 versus 1000 IU of daily oral vitamin D3 doses on vitamin D levels and anthropometric measurements of two groups of newborns. A Randomized controlled trial included eighty successive preterm neonates with a gestational age of ?32 weeks who were randomly allocated to receive 400 or 1000 IU/day of vitamin D. Data were processed using the Statistical Package for Social Science version 23. Vitamin D concentrations at 40 weeks postconceptual age were significantly higher in the 1000 IU (16.26 ± 7.92 ng/ml) when compared to the 400 IU group (12.87 ± 6.15 ng/ml). Serum Calcium showed a highly significant rise in the 1000 IU group when compared with the 400 IU group (9.18 ± 1.76 mg/dL vs. 8.69 ± 0.77 mg/dL, p
Databáze: OpenAIRE