Cryopreserved iliac artery allograft for primary arterial revascularization in adult liver transplantation

Autor: Agnès Rode, Siraj Saadaldin Abdullah, Christian Ducerf, Jean-Paul Bourgeot, J. Baulieux, Jean-Yves Mabrut, Assia Eljaafari
Rok vydání: 2011
Předmět:
Zdroj: Clinical Transplantation. 26:E12-E16
ISSN: 0902-0063
Popis: Mabrut J-Y, Abdullah SS, Rode A, Bourgeot J-P, Eljaafari A, Baulieux J, Ducerf C. Cryopreserved iliac artery allograft for primary arterial revascularization in adult liver transplantation. Clin Transplant 2012: 26: E12–E16. © 2011 John Wiley & Sons A/S. Abstract: Arterial allograft represents a material of choice for primary arterial revascularization in liver transplantation (LT) when interposition of a vascular conduit is required. In case of non-availability of such graft, the use of cryopreserved vessels should be an interesting option. Three patients were grafted using a cryopreserved iliac artery allograft (CIAA) previously harvested and stored at −140°C in a tissue bank. An auxiliary partial LT was performed in one patient for acute liver failure. During follow-up, an efficient regeneration of the native hemi-liver was observed while atrophy of the auxiliary graft occurred, leading to functional portal vein and hepatic artery thrombosis at six and nine months, respectively. Two other patients presented with celiac trunk compression because of arcuate ligament without available arterial allograft in the donor. Late arterial thrombosis occurred at six months in one patient without impairment of graft function. The last patient was alive and symptom free 29 months after LT with a patent cryopreserved arterial conduit. Our preliminary results suggest that CIAA might represent an efficient solution as vessel interposition for primary arterial hepatic revascularization in LT setting when no other suitable graft is available. However, long-term patency of CIAA remains questionable.
Databáze: OpenAIRE
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