An efficient synthesis of benzo[b]benzofurano[2,3-e]-[1,6]naphthyridine-8-ones

Autor:	Wei Zhao, Yong-Yang Wang, Jian-Ying Wu, Dan Wu, Dao-Lin Wang
Rok vydání:	2015
Předmět:	Stereochemistry Chemistry General Chemistry Alkylation Medicinal chemistry Isomerization Catalysis
Zdroj:	Chinese Chemical Letters. 26:251-254
ISSN:	1001-8417
DOI:	10.1016/j.cclet.2014.11.005
Popis:	An efficient method for the synthesis of benzo[b]benzofurano[2,3-e][1,6]naphthyridine-8-one derivatives has been developed via Pictet-Spengler reaction of 4-(3-aminobenzofuran-2-yl)quinoline-2-ones, which could be obtained from alkylation of 4-bromomethylquinoline-2-ones with salicylonitrile and subsequent Thorpe-Ziegler isomerization, with aromatic aldehydes under p-TsOH as catalyst in good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::656942e119b63617fe476640929ed41d https://doi.org/10.1016/j.cclet.2014.11.005 Zobrazit plný text záznamu Full Text from ScienceDirect