| Autor: | Marc Bijl, E.C. Hagen, Tom W J Huizinga, A.W.L. van den Wall Bake, Gerry Ligtenberg, F. H. J. Van Den Hoogen, J.W. de Glas-Vos, J.C. van Houwelingen, Cecile Grootscholten, R.H.W.M. Derksen, Karlein M.G. Schreurs, F. J. Snoek, Jhm Berden |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Systemic lupus erythematosus Lupus erythematosus business.industry Concurrent validity Public Health Environmental and Occupational Health Lupus nephritis medicine.disease Checklist Quality of life Cronbach's alpha immune system diseases Internal medicine Rheumatoid arthritis Physical therapy medicine skin and connective tissue diseases business |
| Zdroj: | Quality of Life Research. 12:635-644 |
| ISSN: | 0962-9343 |
| DOI: | 10.1023/a:1025176407776 |
| Popis: | Reliable and sensitive measures are needed to evaluate the quality of life (QoL) in patients with systemic lupus erythematosus (SLE). No lupus specific questionnaires are available. This study describes the development and validation of a disease-specific questionnaire for lupus patients, which assesses the presence and burden of 38 disease- and treatment-related symptoms: the SLE Symptom Checklist (SSC). Reliability and reproducibility were tested in respectively 87 and 28 stable SLE patients. The internal consistency (Cronbach's alpha coefficients 0.89) and test-retest reliability (Pearson product-moment correlation coefficient between 0.67 and 0.87) were satisfactory. Concurrent validity was supported by significant, but moderate correlations with other measures of subjective well-being and functional status. Responsiveness was measured in 17 patients with lupus nephritis treated with cyclophosphamide, at start of therapy and 1 year thereafter. A significant change in number of symptoms and total distress level was found. It is concluded that the SSC has satisfactory psychometric properties and appears suitable for both clinical and research purposes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink