Study to assess the status of bupivacaine hydrochloride in the management of essential trigeminal neuralgia
Autor: | Sojeeb Dhar, Shohda Khatun, Ashis Kumar Biswas, Rajan Karmakar, Mst. Mahbuba Kafia Parvin |
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Rok vydání: | 2014 |
Předmět: |
Bupivacaine
medicine.medical_specialty Medical treatment business.industry Strategy and Management Mechanical Engineering medicine.medical_treatment Significant difference Metals and Alloys medicine.disease Industrial and Manufacturing Engineering Surgery Trigeminal neuralgia Anesthesia Neuropathic pain Nerve block medicine Local anesthesia business Bupivacaine hydrochloride medicine.drug |
Zdroj: | Bangladesh Journal of Physiology and Pharmacology. 26:30-33 |
ISSN: | 2408-8439 1561-1566 |
DOI: | 10.3329/bjpp.v26i1-2.19965 |
Popis: | Trigeminal neuralgia (TN) is a rare form of neuropathic facial pain characterized by severe paroxysmal pain in the face. The treatment of trigeminal neuropathic pain disorder is a major therapeutic challenge. Medical therapy often fails either due to poor responses to drugs or to unacceptable side effects and for those cases local anesthesia should be considered. Twenty patients (nine men and eleven women) who were diagnosed with TN previously and were not responsive to further medical treatment were selected for treatment. For this study, the affected nerve was blocked with 1.5 ml of 0.5% bupivacaine HCl. Patients visual analogue scores (VAS) were recorded on preoperative day and on post operative at day 3, 7days, 15 days. There was a significant difference between mean preoperative and postoperative VAS value. Preoperative value was 83.10± 6.06, at postoperative 3 days was 39.60 ± 7.86, at postoperative 7 days was 16.25 ± 6.46 and at postoperative 15 days was 3.30 ± 3.19. So it can be concluded that administration of 1.5 ml of 0.5% bupivacaine HCl nerve block at regular interval can be used as treatment for patients who are affected by the side effects from high-dose antiepileptic drugs. http://dx.doi.org/10.3329/bjpp.v26i1-2.19965 Bangladesh J Physiol Pharmacol 2010; 26(1&2) : 30-33 |
Databáze: | OpenAIRE |
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