Differential Prevalence and Predictors of Preclinical Diastolic Dysfunction in a Hispanic Population with Type 2 Diabetes Mellitus Based on 2009 versus 2016 ASE Diastolic Function Guidelines

Autor: Cesar Ochoa, Siu-Hin Wan, Fanglong Dong, Andrew S. Pumerantz, Horng H. Chen
Rok vydání: 2019
Předmět:
Zdroj: Journal of Cardiac Failure. 25:S94-S95
ISSN: 1071-9164
Popis: Introduction The prevalence and predictors of undetected pre-clinical diastolic dysfunction (PDD), Stage B heart failure, in the Hispanic population with type 2 diabetes (T2D) is not well defined. In 2016, the American Society of Echocardiography (ASE) recommended a revised diastolic dysfunction categorization guideline. Objectives To identify prevalence and predictors of PDD in Hispanic adults with T2D, and compare differences in clinical and echocardiographic characteristics utilizing 2009 versus 2016 ASE diastolic function guidelines. Methods A cross-sectional study of Hispanic adults with T2D from 2013 to 2016 was performed. Subjects without signs or symptoms of heart failure (HF) underwent 2D/Doppler echocardiography and grouped into two sub-cohorts: 1) normal diastolic function, and 2) PDD, defined by 2009 or 2016 ASE criteria. Univariable and multivariable logistic analysis were performed to identify characteristics associated with PDD. Results Among 307 subjects, by 2009 criteria, 63% and 37% had normal diastolic function and PDD, respectively. By 2016 criteria, 85%, 7%, and 8% had normal diastolic function, PDD, and indeterminate diastolic function, respectively. Those with PDD were older (mean age 59.1±12.7 vs 52.2±12.2 years, p Conclusions By utilizing 2016 versus 2009 diastolic function criteria to a Hispanic population with T2D, the prevalence of PDD decreased from 37% to 7%, consistent with the new guidelines being more specific and less sensitive for diagnosing PDD.
Databáze: OpenAIRE
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