Autor:	Ernest Beutler, Carol West, N. V. Paniker
Rok vydání:	1971
Předmět:	Sickle Hemoglobin Biochemistry Chemistry Immunology Biophysics Saturation vapor curve Cell Biology Hematology Saturation (chemistry)
Zdroj:	Blood. 37:184-186
ISSN:	1528-0020 0006-4971
DOI:	10.1182/blood.v37.2.184.184
Popis:	Red cells were depleted of 2,3-diphosphoglycerate (2,3-DPG) by storage in acid-citrate-dextrose (ACD) solution. No change in the sickling-oxygen saturation curve was observed. 2,3-DPG did not affect the viscosity of deoxygenated sickle hemoglobin solutions. It appears, then, that the interaction between 2,3-DPG and sickle hemoglobin does not produce configuration changes which influence the aggregation leading to sickling.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::653c75296ddd01de1851872bb92bf18e https://doi.org/10.1182/blood.v37.2.184.184 Zobrazit plný text záznamu