| Popis: |
The theoretical model for self sustained potential oscillation of lipid bilayer membrane induced by gel–liquid crystal phase transitions, given by Yagisawa et al. (Biophys. J. 64 (1993) 1461), has been experimentally investigated using liquid membrane bilayer system. The data do not corroborate the postulate of gel–liquid crystal phase transition, induced by the repetitive adsorption and desorption of protons by the membrane surface. For example, in the proposed model no external stimulus like externally applied electric current is necessary for the occurrence of self sustained oscillations, whereas in the present experiments no oscillations were observed unless an external current of magnitudes ≥2.4 mA, with the compartment having higher H + ion concentrations as negative was passed through the membrane. The model though theoretically self consistent does not seem to correspond to the actual reality at least in the liquid membrane bilayer system presently studied. |
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