SYNTHESIS OF AMIDINE AND BIS AMIDINE PERCURSORS

Autor: Nidhi Singhal, Sham M. Sondhi, Monika Johar, J. W Lown
Rok vydání: 2001
Předmět:
Zdroj: Phosphorus, Sulfur, and Silicon and the Related Elements. 174:81-92
ISSN: 1563-5325
1042-6507
DOI: 10.1080/10426500108040234
Popis: The reactions of substituted o-phenylene diamines, o-aminophenol, o-aminothiophenol, 3,4-diaminopyridine with p-cyanobenzaldehyde by refluxing in nitrobenzene gave corresponding benzimidazole, benzoxazole, benzthiazole and imidazopyridine derivatives Ia,b, II, III, and IV, respectively. Reaction of 4,5-diaminopyrimidine with p-cyanobenzaldehyde gave only Schiffs base it. V or V′ and not imidazopyrimidine derivative, 2,6-Pyridine dialdehyde on condensation with p-aminobenzonitrile give corresponding dicyano compound VI. In an attempt to couple p-aminobenzonitrile with 2,6- pyridine dicarboxylic acid using dicyclohexyl carbodiimide or 1,1′-carbonyl diimidazole, only intermediates VII & VIII were obtained, respectively and no coupled product wax formed.
Databáze: OpenAIRE