| Popis: |
INTRODUCTION: we aimed to predict treatment success with comparing B-hcg values on first and fourth days of methotrexate injection METHODS: we research the informations of ectopic pregnancy, retrospectively, between years 2009 and 2017 in Kartal Dr.Lutfi Kirdar Training and Research Hospital which treated with single dose MTX. 183 patients included into the study. RESULTS: In our study; 77,6% of patients treated with single dose MTX injection. With inclusion of second dose injected patients, success rate is rising to 91,8%. When we look at the prior B-hcg values, patients,those have less than 2000 mIU/mL values, have higher treatment success rate with single dose MTX injection. When we look at the patients, who needed second MTX dose, we have seen 95,95% success rate on patients’ B-hcg values less than 4000 mIU/mL. More than 10 percent decrease of Patients’ B-hcg value between first and fourth days of treatment showed 94,6% success rate. As patients’ treatment,whose B-hcg values decreased less than 10%, showed 48,6% success rate. DISCUSSION AND CONCLUSION: Despite treatment success rate as initial B-hcg levels rises, we have to keep in mind that even patients with higher than 5000 mIU/mL B-hCG, there is a 72% treatment success rate. If there is no contraindication, still MTX treatment considered as a good choice of treatment. More than 10 percent decrease on patients’ fourth day of treatment B-hcg values seems to be a good parameter for treatment success prediction. But there is 48,6% of negative predictive value, and this is a disadvantage about prediction of MTX injection treatment success. |
