GLUCOSE LEVEL ANALYSIS ON STORED PACKED RED CELLS

Autor:	Rachmawati Muhiddin, Melissa Heidy Wongsari, Mansyur Arif
Rok vydání:	2018
Předmět:	Red cell metabolism Packed Red Cells business.industry Metabolism Lactic acid chemistry.chemical_compound Animal science chemistry General Earth and Planetary Sciences Medicine Glycolysis Blood bank refrigerator Decreased ph business General Environmental Science
Zdroj:	INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 24:117-121
ISSN:	2477-4685 0854-4263
DOI:	10.24293/ijcpml.v24i2.1308
Popis:	The main source of energy for red cell metabolism is glucose via glycolytic pathway. Red cells metabolism slows down during storage at 2–6OC. Biochemical changes during storage are called storage lesions, i.e. decreased pH, glucose, and ATP, lactic acid accumulation, and loss of red cells function. Samples taken from the tip of PRC bags in CPDA-1 of the same code are divided into four sections, and stored in the blood bank refrigerator at 2–6OC. Glucose level is measured using ABX Pentra 400 (Horiba, Japan) on storage day 3 as a control, day 7, day 14, and day 21. Glucose levels during storage decreased significantly between day 3, and day 7 (p < 0.001), between day 7, and day 14 (p < 0.001), and between day 14, and 21 (p < 0.001). Glucose levels of Packed Red Cells (PRC) decrease during storage. Glycolysis occurs during storage although metabolism slows down.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::64ce52d4f00723b59d27dd743408f511 https://doi.org/10.24293/ijcpml.v24i2.1308 Zobrazit plný text záznamu