Efficient Pd-Catalyzed Hydrodehalogenation of o-Haloanilides in Water

Autor:	Ze-Wei Mao, Gaoxiong Rao, Hui Gao, Minxin Li, Yanling Tang
Rok vydání:	2020
Předmět:	010405 organic chemistry Aryl Organic Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Chloride 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Bromide Functional group medicine medicine.drug
Zdroj:	Synlett. 31:1121-1125
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0040-1707116
Popis:	In the present work, we have developed a practical methodology for the hydrodehalogenation of o-haloanilides using PdCl2 at 100 °C under mild conditions in water. The catalytic system could selectively dehalogenate both aryl chloride and aryl bromide and exhibit a broad functional group tolerance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::64b6a8d01c3d4e25f9afffcaf207c8c8 https://doi.org/10.1055/s-0040-1707116 Zobrazit plný text záznamu