Endogenous colony formation in mice under the influence of Mycoplasma arthritidis and Rauscher leukemia virus

Autor: A. V. Sanin, A. V. Pronin, I. V. Rakovskaya, V. V. Khorobrykh, G. Ya. Kagan, D. R. Kaulen
Rok vydání: 1979
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 88:874-877
ISSN: 1573-8221
0007-4888
Popis: Mycoplasmaarthritidis was shown not to affect endogenous colony formation in lethally irradiated BALB/c mice. The number of endogenous foci in mice irradiated in sublethal doses and infected withM.arthritidis was sharply increased when the mycoplasma was injected 24 h before or 4 h after irradiation. Mixed infection of (C57BL/6×A/Sn)F1 mice resistant to Rauscher virus with this virus and mycoplasma led to a marked increase in the number of endogenous colonies in the early stages of infection. This phenomenon may perhaps lie at the basis of the loss of resistance in the hybrid mice and the appearance of leukemia in them as a result of mixed infection with mycoplasma and virus.
Databáze: OpenAIRE