Plausibility of the combination of 17 α hydroxyprogesterone injection and Nifedipine versus Magnesium sulfate in the management of preterm labor, RCT
| Autor: | Amina Nagy Elasy, Ahmed Mahmoud Farag, Amr Mostafa Kamel Aboelfath |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International journal of health sciences. :659-669 |
| ISSN: | 2550-696X 2550-6978 |
| DOI: | 10.53730/ijhs.v6ns10.13602 |
| Popis: | Background: Preterm birth is the leading cause of neonatal mortality and the most common reason for neonatal admission to the hospital. Although the causes of preterm labor are not well understood, the burden of preterm births is clear—preterm births account for approximately 70% of neonatal deaths and 36% of infant deaths as well as 25–50% of cases of long-term neurologic impairment in children. Objective: To compare the effectiveness of the tocolytic action of the standard protocol of Magnesium sulfate versus the combination of Nifedipine and 17 α hydroxyprogesterone injection in the term of acute tocolysis therapy on the perinatal outcome and to abrupt threatened preterm labor between 24 weeks to 33 weeks and 6 days. Patients and methods: A prospective randomized control trial study conducted at Zagazig Maternity Hospital, included 102 pregnant women who presented with threatened preterm labor at the Emergency Department of Zagazig University Maternity Hospital. The participants were divided into two groups, group (1) included 51 cases who received the standard protocol of Magnesium Sulfate: loading dose 4 g IV; maintenance 2 g/hr for 24 hrs. |
| Databáze: | OpenAIRE |
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