Asymmetric synthesis of amines using a chiral, non-racemic, cyclic sulphinamide
Autor: | David R.J. Hose, Martin Wills, Tony M. Raynham |
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Rok vydání: | 1993 |
Předmět: | |
Zdroj: | Tetrahedron: Asymmetry. 4:2159-2162 |
ISSN: | 0957-4166 |
DOI: | 10.1016/s0957-4166(00)80065-8 |
Popis: | The homochiral cyclic sulphinamide S(S)R-(+)-1 has been employed in the asymmetric synthesis of α-methylbenzylamine via the benzylidene sulphinamide R(S)Ri-(−)-3. Following diastereoselective reduction and hydrolysis S(S)R-(+)-1 can be recycled in one step from the sulphinic acid 6. |
Databáze: | OpenAIRE |
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