ChemInform Abstract: Double Michael Addition/Aza-Cyclization: A Valuable Sequence for the Construction of Symmetrical and Unsymmetrical Spirobarbiturate-Pyridines

Autor:	Samuele Lillini, Lucia De Crescentini, Orazio A. Attanasi, Fabio Mantellini, Gianfranco Favi, Linda A. Campisi, Fabrizio Ursini
Rok vydání:	2016
Předmět:	Stereochemistry Chemistry Simple (abstract algebra) fungi Michael reaction General Medicine Sequence (medicine)
Zdroj:	ChemInform. 47
ISSN:	0931-7597
DOI:	10.1002/chin.201601099
Popis:	A simple one-pot procedure for the preparation of symmetrical bis-hydrazone functionalized barbiturates, and a step-by step sequence for the synthesis of analogous unsymmetrical derivatives were developed. Their treatment in acid conditions furnish the symmetrical- and unsymmetrical-spirobarbiturate-pyridines, respectively.
Databáze:	OpenAIRE
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