Synthesis of functionalised isochromans: epoxides as aldehyde surrogates in hexafluoroisopropanol
Autor: | Cyprien Muller, Filip Horký, Marie Vayer, Andrei Golushko, David Lebœuf, Joseph Moran |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Chemical Science. 14:2983-2989 |
ISSN: | 2041-6539 2041-6520 |
Popis: | The use of epoxides as aldehyde surrogates allows isochromans to be constructed with greater scope than previously reported oxa-Pictet–Spengler reactions. The initial Meinwald rearrangement and subsequent steps are promoted by HFIP and triflic acid. |
Databáze: | OpenAIRE |
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