Prognostic Implications of Low Level Cardiac Troponin Elevation Using High-Sensitivity Cardiac Troponin T
| Autor: | Naveen Deenadayalu, Marc P. Bonaca, Marc S. Sabatine, David A. Morrow, Eugene Braunwald, Erin Bohula-May, L. Kristin Newby, Petr Jarolim, Jonathan Grinstein, Robert P. Giugliano, Michael J. Conrad |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Acute coronary syndrome Framingham Risk Score Cardiac troponin business.industry medicine.medical_treatment General Medicine Thrombolysis medicine.disease Confidence interval Increased risk Troponin complex Internal medicine medicine Cardiology Myocardial infarction Cardiology and Cardiovascular Medicine business |
| Zdroj: | Clinical Cardiology. 38:230-235 |
| ISSN: | 0160-9289 |
| Popis: | Background High-sensitivity cardiac troponin T (hsTnT) is used in many countries, but is not available in the United States. Prior evidence has been viewed as inconclusive as to whether low cardiac troponin T (cTnT) concentrations detected with hsTnT are prognostically meaningful compared with fourth-generation cTnT. Hypothesis The aim of this study was to assess the prognostic performance of low-level cTnT elevations using the hsTnT assay compared with the assay (fourth-generation) currently available in the United States. Methods We measured serum cTnT in 4160 patients with non–ST-elevation acute coronary syndrome using both the hsTnT and fourth-generation assays. Patients were stratified at the 99th percentile cut point for each assay. Results Patients with baseline hsTnT ≥14 ng/L (n = 3697) vs |
| Databáze: | OpenAIRE |
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