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The prognostic potential of apparent diffusion coefficient (ADC) mapping was studied as complemented by high-resolution 3D T1-weighted MRI in the assessment of dentin-pulp complex response to caries. Twenty-six extracted human teeth, with or without caries lesions of different grades in accord with the International Caries Detection and Assessment System (ICDAS), were analyzed by high-resolution MRI at 2.35 T. A signal rise in demineralized hard dental tissues in high-resolution T1-weighted MR images enabled assessment of the demineralization depth over the whole range of ICDAS scores. ADC maps of the teeth were calculated from corresponding diffusion-weighted images of four different b values: 0, 132, 317, 635 s/mm2. These maps enabled reliable differentiation between intact (ADC > 1.0·10-9 m2/s) and affected (ADC |
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