Penicillin G production by immobilized fungal vesicles

Autor:	W. Kurzątkowski, Alina Paszkiewicz, W. Kuryłowicz
Rok vydání:	1982
Předmět:	Calcium alginate Vesicle General Medicine Protoplast Biology Penicillium chrysogenum biology.organism_classification Applied Microbiology and Biotechnology Microbiology Penicillin chemistry.chemical_compound Chemically defined medium Biochemistry chemistry medicine Biotechnology medicine.drug
Zdroj:	European Journal of Applied Microbiology and Biotechnology. 15:211-213
ISSN:	1432-0614 0171-1741
DOI:	10.1007/bf00499957
Popis:	The activity of penicillin G production was compared in a well defined medium by native vesicles as well as by calcium alginate gel immobilized vesicles isolated from the protoplasts of Penicillium chrysogenum PQ-96. The activity yield of the immobilized vesicles was 44% in comparison with native vesicles. After 60 h of storage at 4° C the native vesicles showed a rapid decrease in penicillin G production. The storage stability of these vesicles was improved after entrapment inside the calcium alginate gel. After 240 h of storage 1 mg of immobilized vesicular protein catalyzed the production of about 140 nmoles of penicillin G in 1 h.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::643e511633d2856d374c5f78e65394e4 https://doi.org/10.1007/bf00499957 Zobrazit plný text záznamu Full text from SpringerLink