Preliminary study on the central nervous system depressant effect of Picrorhiza kurrooa Royle. (Scrophulariaceae) in mice models
| Autor: | Mahmud Tareq Hassan Khan, Sultana Rajia, Khandaker Ashfaqur Rahman, Mahiuddin Alamgir, T. Rahman, M Shahabuddin Kabir Choudhuri |
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| Rok vydání: | 2008 |
| Předmět: |
Sleeping time
Hole-board test Pentobarbital biology Traditional medicine medicine.drug_class Scrophulariaceae business.industry Central nervous system Pharmacology biology.organism_classification medicine.anatomical_structure Complementary and alternative medicine Picrorhiza kurrooa medicine Depressant business Diazepam medicine.drug |
| Zdroj: | Oriental Pharmacy and Experimental Medicine. 8:448-451 |
| ISSN: | 1598-2386 |
| Popis: | Picrorhiza kurrooa Royle. is a well known medicinal plant among the indigenous medical practitioners of India. Present study is the first time to report the activity on the central nervous system. Preliminary study of the hot water extract showed significant depressant activity on the hole board test as evidenced from the ambulation and head dipping scores. The extract showed better activity compared to diazepam on the duration of pentobarbital induced sleeping time. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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