Prevalence of abnormal glycemic and lipidemic status in an urban population of Bangladesh

Autor: Liaquat Ali, M Khalequzzaman, Ramendu Parial, M Das, Z Hassan, O Faruque
Rok vydání: 2012
Předmět:
Zdroj: Journal of Bio-Science. 19:1-6
ISSN: 2408-8595
1023-8654
DOI: 10.3329/jbs.v19i0.12674
Popis: Context: Undiagnosed cases of diabetes mellitus constitute a major proportion of diabetic patients in the developing countries due to lack of proper screening and primary care facilities. Generation of evidence on undiagnosed cases is highly important for the estimation of the true burden of this disease. Objectives: The present study was undertaken to explore the proportion of undiagnosed diabetes and associated disorders in a middle aged Bangladeshi population living in the capital city of Bangladesh. Materials and Methods: Under a cross-sectional observational design a group of 254 middle aged (35-60 yrs) subjects (146♂ and 108) were included in the study who previously were unaware about the existence of diabetes or its complications. A 2-sample OGTT was done and blood glucose was estimated by glucose-oxidase method and Serum total cholesterol, HDL and TG by enzymatic colorimetric (Cholesterol Oxidase /Peroxidase, CHOD-PAP) method. Glycemic and other abnormalities were diagnosed and classified as per WHO criteria. Results: Out of the total 254 subjects 34 (15.1%) were found to have type 2 diabetes mellitus (T2DM) and 49 (19.29%) were prediabetics (24.5%-IFG, 75.5% -IGT and 20.4% had combined IFG-IGT). WHR (the indicator of central obesity) was present in higher proportions of diabetic (93.9%) and prediabetics (89.9%) compared to 76.0% control (λ 2 =8.815; p=0.017). Male subjects had significantly higher central obesity compared to females both in the controls (t=3.929; p
Databáze: OpenAIRE