| Autor: |
Patrick A. Stockton, Jeffrey J. Field, Jeff Squier, Keith A. Wernsing |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII. |
| DOI: |
10.1117/12.2546071 |
| Popis: |
In recent years, we demonstrated a new approach to super-resolution microscopy based on driving a nonlinear interaction with a Spatial Frequency Modulated Imaging (SPIFI). SPIFI is a line imaging technique that linearly sweeps all the frequencies supported by the band-pass of the objective lens. Here we introduce a new method of unrestricted super-resolution imaging based on driving saturated absorption in the specimen excitation. The saturated absorption drives harmonic distortions of the spatial frequencies used to illuminate the sample. These harmonics manifest themselves as temporal harmonic frequencies allowing for easy detection and separation of the super-resolution information in the far field. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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