Overall Outcome of Kawasaki Disease
| Autor: | Kwangchul Lee, J.K. Lee, Joo Won Lee, Changsung Son, Youngchang Tockgo |
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| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Pediatric Research. 53:176-176 |
| ISSN: | 1530-0447 0031-3998 |
| Popis: | To assess the overall outcome of Kawasaki disease, patients with a discharge diagnosis of Kawasaki disease at Korea University Medical Center from 1999 to 2001 were retrospectively evaluated. A total of 99 patients were diagnosed. The American Heart Association (AHA) criteria were met in 65 patients (66%) and 63 of them received intravenous immune globulin (IVIG, 2g/kg). Fifty patients responded afebrile within 5 days (IVIG-responsive) and 13 patients did not (IVIG-non-responsive). Within 2 months, 2 patients in the IVIG-responsive group developed coronary abnormalities compared to 3 patients in the IVIG-non-responsive group (4% vs 23%). None of whom met AHA criteria and did not received IVIG were febrile more than 5 days nor developed coronary abnormalities. In 34 patients who did not meet complete AHA criteria, 28 patients received IVIG and 25 patients were IVIG-responsive. Coronary abnormalities were developed in 4 in the IVIG-responsive group compared to none in the IVIG-non-responsive group (16% vs 0%). All 6 patients who did not meet complete AHA criteria and did not received IVIG were febrile more than 5 days and 2 of them developed coronary abnormalities. Taken together, coronary abnormalities were developed in 9 patients of 91 who were treated with IVIG compared to 2 patients of 8 who were not treated with IVIG (10% vs 25%). In conclusion coronary abnormalities were developed in 11 of 99 patients with Kawasaki disease (11%). |
| Databáze: | OpenAIRE |
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