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Transgender adolescent healthcare is a relatively novel part of endocrine medicine. Treatment protocols have emerged since the late1990’s and outcome data have become available more recently. A multidisciplinary approach with psychology and endocrinology is required to accommodate the specific needs of developing transgender adolescents and their primary caretakers. Therefore, treatment is ideally provided by specialized centres. However, with a growing population in numbers, all physicians should be familiar with treatment protocols. The endocrine treatment of transgender youth differs from that of transgender adults. The first step of treatment is a phase of gonadal suppression using either gonadotropin hormone-releasing hormone analogues (GnRHa) or, alternatively, progestogens, or antiandrogens. Second step is the induction of sexual characteristics of the affirmed gender using synthetic sex steroids in increasing dosages to mimic a pubertal fase. These specific therapeutics approaches of the transgender adolescent are outlined in this chapter. |
