Direct proof of propionate involvement in choline synthesis in rats

Autor: I. M. Staviskii, E. K. Alimova, A. T. Astvatsatur'yan
Rok vydání: 1983
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 96:1535-1536
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00835280
Popis: Choline, which belongs to the vitamins group, is a biologically important substance found in animals [5, 6]. Endogenous choline is formed in animals by the transfer of methyl groups from three S-adenosylmethionine molecules to the amino group of the ethanolamine residue in the structure of phosphatidylethanolamine. As a result of this reaction phosphatidylcholine is formed. However, the endogenous pathway of choline synthesis is insufficient to supply the physiological needs of the body, and for that reason choline intake in the diet is essential.
Databáze: OpenAIRE