Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist

Autor:	Ruth A. Ross, Lesley A. Stevenson, Maria Grazia Cascio, Roger G. Pertwee, Lisa Anne Gauson
Rok vydání:	2009
Předmět:	Pharmacology Agonist medicine.medical_specialty Cannabinoid receptor medicine.drug_class Cannabigerol Chemistry medicine.medical_treatment Antagonist Receptor antagonist Endocrinology Internal medicine medicine 5-HT1A receptor Cannabinoid Cannabidiol medicine.drug
Zdroj:	British Journal of Pharmacology. 159:129-141
ISSN:	0007-1188
DOI:	10.1111/j.1476-5381.2009.00515.x
Popis:	Background and purpose: Cannabis is the source of at least seventy phytocannabinoids. The pharmacology of most of these has been little investigated, three notable exceptions being Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. This investigation addressed the question of whether the little-studied phytocannabinoid, cannabigerol, can activate or block any G protein-coupled receptor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::63f92ef65341a91684c821677c62405a https://doi.org/10.1111/j.1476-5381.2009.00515.x Zobrazit plný text záznamu Plný text