Numerical analysis of stationary solutions of systems with delayed argument in mathematical immunology

Autor: M. Yu. Khristichenko, Yu. M. Nechepurenko, D. S. Grebennikov, G. A. Bocharov
Rok vydání: 2022
Předmět:
Zdroj: Contemporary Mathematics. Fundamental Directions. 68:686-703
ISSN: 2949-0618
2413-3639
DOI: 10.22363/2413-3639-2022-68-4-686-703
Popis: This work is devoted to the technology developed by the authors that allows one for fixed values of parameters and tracing by parameters to calculate stationary solutions of systems with delay and analyze their stability. We discuss the results of applying this technology to Marchuk-Petrov's antiviral immune response model with parameter values corresponding to hepatitis B infection. The presence of bistability and hysteresis properties in this model is shown for the first time.
Databáze: OpenAIRE