212Pb/212Bi Generator for nuclear medicine

Autor:	M. A. Proshin, V. I. Nikolaev, S. P. Vesnovskii, A. S. Zakharov, A. V. Shatrov, P. P. Boldyrev, D. Yu. Chuvilin, V. A. Zagryadskii, A. I. Bortash
Rok vydání:	2012
Předmět:	Generator (computer programming) Materials science Nuclear Energy and Engineering Tandem Ion exchange Nuclear engineering Extraction (chemistry) Charge (physics) Isotopes of thorium
Zdroj:	Atomic Energy. 111:422-427
ISSN:	1573-8205 1063-4258
Popis:	A scheme for producing the α-emitters 212Pb and 212Bi, to be used in a promising method of diagnostics and therapy in oncology – radioimmunotherapy, is proposed. The technology is based on two generators operating in tandem: 228Th/212Pb and 212Pb/212Bi. The first one is based on separation from an initial solution containing thorium isotopes and gaseous 220Rn, which secures the purity of the desired products 212Pb and 212Bi. For a 228Th/212Pb model generator, the efficiency of 220Rn extraction from solution was ~60%. After conditioning, the 212Pb solution from the 228Th/212Pb generator was used to charge a column, which functioned as a 212Pb/212Bi generator, with a cation exchanger.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::63de7d4d9a998e42c516a3259f340172 https://doi.org/10.1007/s10512-012-9513-x Zobrazit plný text záznamu Full text from SpringerLink