A comparative study for evaluation of cognitive function in type-II diabetes mellitus patients and non-diabetics

Autor: J Ezhil Ramya, B Sriviruthi, A Dulcie Celia
Rok vydání: 2018
Předmět:
Zdroj: International Journal of Basic & Clinical Pharmacology. 7:738
ISSN: 2279-0780
2319-2003
DOI: 10.18203/2319-2003.ijbcp20181179
Popis: Background: To evaluate the impact of type-II diabetes mellitus on cognitive function and to assess the factors associated with impaired function.Methods: This prospective study compared 100 type-II diabetic people attending the diabetic clinic of Tirunelveli Medical College Hospital with another 100 membered control group. The study group was selected randomly between the age group of 45-65 years. A neuro-cognitive assessment was done using Standardized Mini Mental State Examination (SMMSE), which is a simple and reliable screening test. This scale has 12 questions with time limits to assess orientation, memory, calculation, language, attention and construction. Magnitude and severity of cognitive decrement were analysed along with the possible factors affecting it.Results: Mean age of the study population was 54.6±7.24 years. Cognitive impairment was noted among 62 of cases and 48 of the control group, which means a 14% higher prevalence of cognitive impairment among the type 2 diabetics. The association of development of cognitive impairment and duration of diabetes mellitus was significant statistically (p value = 0.025443; p
Databáze: OpenAIRE