Phase I trial of z-endoxifen with estrogen receptor imaging in adults with advanced hormone receptor–positive solid tumors including desmoid and gynecologic tumors

Autor: Naoko Takebe, James H. Doroshow, Frank Lin, Mary Flanagan Quinn, Matthew P. Goetz, Joel M. Reid, Shivaani Kummar, Jerry M. Collins, Alice P. Chen, Nancy Moore, Richard Piekarz, Peter L. Choyke, Esther Mena, Lamin Juwara, Geraldine O'Sullivan Coyne, Howard Streicher, Renee M. McGovern, Liza Lindenberg, Lyndsay Harris, Joseph M. Covey
Rok vydání: 2018
Předmět:
Zdroj: Journal of Clinical Oncology. 36:2516-2516
ISSN: 1527-7755
0732-183X
DOI: 10.1200/jco.2018.36.15_suppl.2516
Popis: 2516Background: Differential response to tamoxifen observed in patients (pts) with hormone receptor-positive cancer may be due to variations in tamoxifen metabolism from CYP2D6 genetic polymorphism...
Databáze: OpenAIRE