A DNA damage-responsive Drosophila melanogaster gene is also induced by heat shock

Autor:	Minton Kw, Smith, Vivino Aa
Rok vydání:	1986
Předmět:	Regulation of gene expression HSPA4 Heat shock factor Restriction map HSPA14 DNA damage Heat shock protein Cell Biology Biology Drosophila melanogaster biology.organism_classification Molecular Biology Molecular biology
Zdroj:	Molecular and Cellular Biology. 6:4767-4769
ISSN:	1098-5549 0270-7306
DOI:	10.1128/mcb.6.12.4767
Popis:	A gene isolated by screening Drosophila melanogaster tissue culture cells for DNA damage regulation was also found to be regulated by heat shock. After UV irradiation or heat shock, induction is at the transcriptional level and results in the accumulation of a 1.0-kilobase polyadenylated transcript. The restriction map of the clone bears no resemblance to the known heat shock genes, which are shown to be uninduced by UV irradiation.
Databáze:	OpenAIRE
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