The preclinical stage of movement disorders
| Autor: | Olaf Eberhardt, Helge Topka |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Movement disorders business.industry 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Neurology Intervention (counseling) medicine Neurology (clinical) medicine.symptom Subclinical disease Intensive care medicine business Preclinical stage Neuroscience 030217 neurology & neurosurgery Disease staging |
| Zdroj: | Basal Ganglia. 6:35-44 |
| ISSN: | 2210-5336 |
| DOI: | 10.1016/j.baga.2015.11.002 |
| Popis: | Findings from both cross-sectional and longitudinal studies have indicated a long preclinical period characterizing most neurodegenerative diseases. The study of presymptomatic movement disorders has implications for our understanding of their pathophysiology, early functional compensation and subclinical disease progression. This might lead to earlier diagnosis, might shift current disease staging and might help define at-risk populations amenable to preventive or disease-modifying therapeutic intervention. Here, we provide an up-to-date overview of the current knowledge about the preclinical stages of common movement disorders. |
| Databáze: | OpenAIRE |
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