Fabrication, characterization and in vitro release kinetics of tofacitinib-encapsulated polymeric nanoparticles: a promising implication in the treatment of rheumatoid arthritis

Autor:	Asif Mahmood, Muhammad Akram, Rai Muhammad Sarfaraz, Muhammad Naeem Qaisar, Muhammad Aamir, Zahid Hussain, Sajid Bashir, Muhammad Umer Sarwer
Rok vydání:	2020
Předmět:	Tofacitinib Fabrication Polymers and Plastics Chemistry General Chemical Engineering Rheumatoid arthritis Kinetics medicine medicine.disease Polymeric nanoparticles Combinatorial chemistry In vitro Analytical Chemistry
Zdroj:	International Journal of Polymeric Materials and Polymeric Biomaterials. 70:449-458
ISSN:	1563-535X 0091-4037
DOI:	10.1080/00914037.2020.1725760
Popis:	Despite exhibiting remarkable efficacy for treatment of rheumatoid arthritis, clinical applicability of tofacitinib (TFC) is limited owing to its short plasma half-life. Therefore, this study was a...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::63c34d4b90ecab14a2860a06523175f1 https://doi.org/10.1080/00914037.2020.1725760 Zobrazit plný text záznamu