| Popis: |
Precision medicine is a relatively new field, based on the hypothesis that genetic predispositions influence an individual’s response to specific interventions such as diet, exercise, supplements and prescription medications. Despite the increase in commercially available genomic testing, few studies have investigated the effect of a physician-directed program to optimize health using genomics-based precision medicine. We performed an observational cohort study to evaluate the effect of the Wild Health program, a physician and health coach service offering genomics-based lifestyle interventions and supplement recommendations, on biomarkers indicative of chronic disease. Patients underwent genomic testing, biomarker testing, and a full evaluation by physicians and health coaches, with ongoing health coaching after the initial medical consultation. Improvements in several clinically relevant out-of-range biomarkers at baseline were identified in patients treated through lifestyle intervention without the use of prescription medication. Notably, normalization of several out-of-range biomarkers associated with chronic disease occurred in 47.5% (hemoglobin A1c [HbA1c]), 33.3% (low density lipoprotein particle number [LDL-P] , and 33.2% (C-reactive protein [CRP]). |
