Mucosus Organism from Suppurative Lesions of Rat on Diet Deficient in Vitamin A
| Autor: | William L. Bradford |
|---|---|
| Rok vydání: | 1928 |
| Předmět: |
Vitamin
medicine.medical_specialty Cellular activity business.industry Physiology medicine.disease chemistry.chemical_compound Infectious Diseases Otitis Endocrinology medicine.anatomical_structure chemistry Internal medicine medicine Immunology and Allergy medicine.symptom Sinusitis business Organism Respiratory tract |
| Zdroj: | Journal of Infectious Diseases. 43:407-414 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/43.5.407 |
| Popis: | Spontaneous infection of the upper part of the respiratory tract of the albino rat is not uncommon. In animals being used for experimental purposes, as well as among those kept in stock 1 one frequently encounters suppurative otitis media, purulent nasal sinusitis, and various types of pulmonary infections. As terminal events in the course of experimental avitaminosis in the white rat, such infections are frequent 2 and are instrumental in causing death. It is thought that deficiency of vitamin A causes such a reduction in cellular activity that it amounts to a deficiency of glandular activity 3 and that this, in turn, brings about secondary changes, bacterial invasion, and death. Reviewing the literature, one is surprised to find that bacteriologic studies of these infections have not been extensive. For this reason, and because it was desired to find an organism in rats kept on diets deficient in vitamin A that might be suitable for use in the study of the relationship of vitamin deficiencies to infection, cultural studies of a group of animals dying from avitaminosis, were made. Method of Culture.-By using ordinary skill one can obtain satisfactory cultures from the middle ears and the nasal turbinates of a rat by the following technique. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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