Synthesis of 14C-labelled (S)-(+)-2-[4-(p-fluorobenzoyl)-1-piperidyl]-1-naphthylethanol hydrochloride
Autor: | R. M. Rosser, Norio Karibe, Hachiro Sugimoto, Masataka Ueda |
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Rok vydání: | 1990 |
Předmět: | |
Zdroj: | Journal of Labelled Compounds and Radiopharmaceuticals. 28:823-830 |
ISSN: | 0362-4803 |
DOI: | 10.1002/jlcr.2580280712 |
Popis: | 14C-labelled (S)-(+)-2-[4-(p-fluorobenzoyl)-1-piperidyl]-1-naphthylethanol hydrochloride (5), an anti-ischemic drug, was synthesized for studying the pharmacokinetic profiles of the compound in four steps using 2-[carbonyl-14C]acetonaphthone (1) as a labelled starting material. |
Databáze: | OpenAIRE |
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