Synthesis of 14C-labelled (S)-(+)-2-[4-(p-fluorobenzoyl)-1-piperidyl]-1-naphthylethanol hydrochloride

Autor: R. M. Rosser, Norio Karibe, Hachiro Sugimoto, Masataka Ueda
Rok vydání: 1990
Předmět:
Zdroj: Journal of Labelled Compounds and Radiopharmaceuticals. 28:823-830
ISSN: 0362-4803
DOI: 10.1002/jlcr.2580280712
Popis: 14C-labelled (S)-(+)-2-[4-(p-fluorobenzoyl)-1-piperidyl]-1-naphthylethanol hydrochloride (5), an anti-ischemic drug, was synthesized for studying the pharmacokinetic profiles of the compound in four steps using 2-[carbonyl-14C]acetonaphthone (1) as a labelled starting material.
Databáze: OpenAIRE