DietarySpirulina platensisalleviates aluminum and aluminum fluoride induced histopathological and biochemical alterations in mice kidney
| Autor: | Nirmala Yadav, K. P. Sharma, Shweta Sharma, Anil Pandey, Subhasini Sharma |
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| Rok vydání: | 2014 |
| Předmět: |
Spirulina (genus)
Aluminum fluoride Kidney medicine.medical_specialty biology Chemistry Health Toxicology and Mutagenesis Histology Pharmacology biology.organism_classification Pollution Nephrotoxicity Prolonged exposure medicine.anatomical_structure Biochemistry medicine Environmental Chemistry Histopathology Water intake |
| Zdroj: | Toxicological & Environmental Chemistry. 96:1106-1119 |
| ISSN: | 1029-0486 0277-2248 |
| DOI: | 10.1080/02772248.2015.1007987 |
| Popis: | Aluminum and its salts widely used in our daily life have been reported nephrotoxic to humans and animals following prolonged exposure. Therefore, the present study was made to examine the renoprotective role of Spirulina platensis against Al3+ and AlF3 in male Swiss albino mice. Exposure to these chemicals decreased feed and water intake, and body and kidney weights. Histology of kidney and their biochemistry were also markedly altered along with that of serum biochemistry. Spirulina not only minimize toxic effects of test chemicals but also favored faster recovery of treated mice after their withdrawal. |
| Databáze: | OpenAIRE |
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