Synthesis and Intramolecular Cyclization of Substituted 4-(Het)aryl-4-oxo-2-thienylaminobut-2-enoic Acids Containing Nitrile Group in the Thiophene Ring

Autor:	I. A. Gorbunova, S. A. Shipilovskikh, Aleksandr E. Rubtsov, D. A. Shipilovskikh
Rok vydání:	2021
Předmět:	chemistry.chemical_compound chemistry Nitrile Propionic anhydride Group (periodic table) Aryl Intramolecular cyclization Thiophene Substituent General Chemistry Ring (chemistry) Medicinal chemistry
Zdroj:	Russian Journal of General Chemistry. 91:1623-1628
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363221090048
Popis:	A method for the synthesis of substituted 4-(het)aryl-4-oxo-2-thienylaminobut-2-enoic acids containing a nitrile substituent in the thiophene ring was proposed. Intramolecular cyclization of the obtained compounds in the presence of propionic anhydride leads to the formation of new substituted 3-thienylimino-3H-furan-2-ones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6372084337afe52354b4ba1ba5352093 https://doi.org/10.1134/s1070363221090048 Zobrazit plný text záznamu